| By anatomy and proximal fixation | Cephalomedullary nail | Proximal femur | A femoral nail with one or more large proximal screws or a blade directed into the femoral head and neck. | Selected intertrochanteric and subtrochanteric fractures, according to fracture pattern and clinical assessment. | Proximal head-and-neck fixation is combined with distal locking screws when indicated. |
| By anatomy and insertion route | Antegrade femoral nail | Femoral shaft; inserted from the proximal femur | A long, curved nail introduced through a proximal entry point and advanced down the femoral medullary canal. | Many femoral shaft fractures. | Interlocking screws can be placed proximally and distally to control length and rotation. |
| By anatomy and insertion route | Retrograde femoral nail | Femoral shaft or selected distal femur; inserted through the knee end of the femur | A nail inserted through a distal femoral entry point, with the available locking options depending on the device and fracture location. | Selected femoral shaft and distal femoral fractures; the approach may be considered when a proximal entry route is unsuitable. | Interlocking screws secure the nail; distal fixation options vary by design. |
| By anatomy | Tibial nail | Tibial shaft | A nail shaped for the tibial canal, with proximal and distal locking options. | Many tibial shaft fractures. | Interlocking screws help maintain alignment, length, and rotation; screw configuration depends on the fracture and nail design. |
| By anatomy and entry route | Humeral nail | Humeral shaft and, for some designs, selected fractures near either end of the humerus | A nail designed for the humeral canal; insertion may be antegrade or retrograde depending on the design and fracture. | Selected humeral shaft fractures. | Proximal and distal locking screws may be used. Entry-point and locking choices depend on the fracture and anatomy. |
| By nail flexibility and patient group | Flexible or elastic intramedullary nail | Most commonly selected long-bone fractures in children | One or more slender, flexible nails are placed in the medullary canal; the technique relies on balanced elastic support rather than a large rigid nail. | Selected pediatric long-bone fractures, with suitability influenced by age, bone size, and fracture pattern. | Usually does not use the same transverse interlocking-screw configuration as a rigid adult nail. |
| By proximal screw orientation | Femoral reconstruction nail | Femur, including shaft fractures with associated proximal femoral involvement | A femoral nail with proximal screw options oriented to provide fixation in the femoral head and neck, in addition to shaft fixation. | Selected combined proximal femoral and shaft fracture patterns. | Proximal head-and-neck screws and distal interlocking screws are used as appropriate to the fracture. |
| By locking configuration | Statically or dynamically locked nail | Design feature used in nails for several long bones | “Static” and “dynamic” describe locking configurations. Depending on the nail, a slot or selected screw position may permit controlled axial movement. | Locking configuration is selected to suit fracture stability, location, and the treatment plan. | Options differ by nail model; not every nail offers the same locking modes. |